Pharmaceutical Biotechnology
Námskeið
- LYF122F Líftæknilyf
Ensk lýsing:
This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pharmaceutical industry. The Fourth Edition will completely update the previous edition, and will also include additional coverage on the newer approaches such as oligonucleotides, siRNA, gene therapy and nanotech.
Lýsing:
This introductory text explains both the basic science, production, quality, dosage forms, administration, economic and regulatory aspects and the clinical applications of biotechnology-derived pharmaceuticals. It serves as a complete one-stop source for undergraduate/graduate pharmacists and pharmaceutical science students. An additional important audience are pharmaceutical scientists in industry and academia, particularly those who have not received formal training in pharmaceutical biotechnology and are inexperienced in this field.
The rapid growth and advances in the field made it necessary to revise this textbook in order to continue providing up-to-date information and introduce readers to cutting edge knowledge and technology of this field. This Sixth Edition completely updates the previous edition and includes additional coverage on new approaches such as oligonucleotides, siRNA, mRNA, gene therapy, cell therapies, monoclonal antibodies and vaccines.
Annað
- Höfundur: Daan J. A. Crommelin, Robert D. Sindelar, Bernd Meibohm
- Útgáfa:6
- Útgáfudagur: 2024-01-29
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- Format:ePub
- ISBN 13: 9783031300233
- Print ISBN: 9783031300226
- ISBN 10: 3031300238
Efnisyfirlit
- Cover
- Front Matter
- Part I. Pharmaceutical Biotechnology: The Science, Techniques, and Important Concepts
- 1. Molecular Biotechnology: From DNA Sequence to Therapeutic Protein
- 2. Biophysical and Biochemical Characteristics of Therapeutic Proteins
- 3. Stability and Characterization of Protein- and Nucleotide-Based Therapeutics
- 4. Production and Purification of Recombinant Proteins
- 5. Formulation of Biologics Including Biopharmaceutical Considerations
- 6. Pharmacokinetics and Pharmacodynamics of Therapeutic Proteins and Nucleic Acids
- 7. Immunogenicity of Therapeutic Proteins
- 8. Monoclonal Antibodies: From Structure to Therapeutic Application
- 9. Genomics, Other “OMIC” Technologies, Precision Medicine, and Additional Biotechnology-Related Techniques
- 10. Economic Considerations in Medical Biotechnology
- 11. Biosimilars: Principles, Regulatory Framework, and Societal Aspects
- 12. An Evidence-Based Practice Approach to Evaluating Biotechnologically Derived Medications
- Part II. Pharmaceutical Biotechnology: Oligonucleotides, Genes and Cells/Cell Subunits, Vaccines—The Science, Techniques, and Clinical Use
- 13. Oligonucleotides and mRNA Therapeutics
- 14. Advanced Therapy Medicinal Products: Clinical, Non-clinical, and Quality Considerations
- 15. Vaccines
- Part III. Pharmaceutical Biotechnology: The Protein Products of Biotechnology and Their Clinical Use—Endogenous Proteins and Their Variations
- 16. Insulin
- 17. Hematopoietic Growth Factors
- 18. Recombinant Coagulation Factors and Thrombolytic Agents
- 19. Follicle-Stimulating Hormone
- 20. Human Growth Hormone
- 21. Recombinant Human Deoxyribonuclease I
- 22. Interferons and Interleukins
- Part IV. Pharmaceutical Biotechnology: The Protein Products of Biotechnology and Their Clinical Use—Monoclonal Antibodies and Their Variations
- 23. Antibody-Based Biotherapeutics in Cancer
- 24. Antibody-Based Biotherapeutics in Inflammatory Diseases
- 25. Monoclonal Antibodies in Solid Organ Transplantation
- 26. Antibody-Based Biotherapeutics in Migraine
- Back Matter
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- Gerð : 208
- Höfundur : 6512
- Útgáfuár : 2019
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